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Laboratory of
Ocular Biomechanics

University of Pittsburgh


New paper accepted

  • "MAPS - a Magic Angle Positioning System for Enhanced Imaging in High-Field Small-Bore MRI"
    by Journal of Medical Robotics Research.

Welcome Spring 2016 Undergraduate Research students

  • Karlie Brasch (FER), Jennifer Panza (FER), Emma Chen (FER), Brienna Roys (FER), Jin Yu Li (FER), Shumeng Yang and Eric Sou Ying Dong

Congratulations Joshua Selling, Morgan Skapik, Nicholas Cox and Rachel Rohr

  • 2nd place in the Swanson School of Engineering Design Expo 2015

Congratulations Cindy Jiao and Jacob Wallace

  • Awarded Brackenridge Fellowships by the University of Pittsburgh Honors College

New Post-Doctoral Position Available

eCover of Biomedical Optics Express

  • "Polarization Microscopy for Characterizing Fiber Orientation of Ocular Tissues" has been selected for the eCover of the December 2015 issue.

New paper accepted

  • "Use And Misuse of Laplace's Law in Ophthalmology"
    by IOVS (Investigative Ophthalmology and Visual Science).

Letter to the editor accepted

  • "A Problem of Proportions in OCT-Based Morphometry and a Proposed Solution"
    by IOVS (Investigative Ophthalmology and Visual Science).

Active projects
Click images for more info.

Why biomechanics of the eye?

In our daily lives we rarely think of the eye as a biomechanical structure. The eye, however, is a remarkably complex structure with biomechanics involved in many of its functions. For our eyes to be able to track moving objects, for example, requires a delicate balance of the forces exerted by several muscles. Forces are also responsible for deforming the lens and allow focusing. A slight imbalance between the forces and tissue properties may be enough to alter or even preclude vision. These effects may take place quickly or over long periods, even years. Understanding ocular biomechanics is therefore important for preventing and treating vision loss.


Eye diagram

Schematic cross-section through a human eye. Light enters the eye through the cornea, passes through the pupil, lens and vitreous humour and strikes the retina, where it is absorbed. Retinal nerve fibers transmit visual information to the brain. These fibers converge at the optic nerve head region, exit the eye through the scleral canal, and form the optic nerve. The lamina cribrosa is a porous structure spanning the scleral canal. The vitreous chamber is filled with the vitreous humor, which exerts a pressure, the intraocular pressure, on the surface of the retina. [Sigal et al. Biomech Model Mechanobiol, 8(2):85-98, Apr 2009] (adapted from an illustration from NIH)



The objective of the Laboratory of Ocular Biomechanics is to study the eye as a biomechanical structure. More specifically our work is aimed at identifying the causes of glaucoma, with the ultimate intention of finding a way to prevent vision loss.