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Laboratory of
Ocular Biomechanics

University of Pittsburgh

POSITIONS

We are always looking for smart and highly motivated people interested in working with us.

Postdocs:
We are interested in recruiting a post-doctoral fellow with experience in image registration and elastography. Please contact us if interested and qualified.

Undergraduate students: We regularly receive undergraduate students from all over Pitt. Many of them come for Design projects (e.g. MEMS 1043) or Intramural Internships (e.g. BIOENG 1002). We also regularly receive students for summer research. Most of them do research associated with coursework, or are volunteers who want experience in research. If you need funding, we can help you apply. Bear in mind that most funding support is very competitive. If interested, send an email to Dr. Sigal. In this email, explain your background and your interest in our lab. Attach your CV or Resume.

Faculty

  • Dr. Ian Sigal

    Ian A. Sigal, Ph.D. - Assistant Professor

    Dr. Sigal received a B.Sc. in Physics from the Universidad Nacional Autónoma de México, México City (1999), a M.A.Sc. in Aerospace Engineering from the University of Toronto, Canada (2001), and a Ph.D. in Mechanical Engineering (Collaborative program in Biomedical Engineering) also from the University of Toronto, Canada (2006). Dr. Sigal has dedicated his scientific career to the study of biomechanics-related diseases of the eye, and to glaucoma in particular. During his PhD he pioneered methods for computational modeling of the eye to understand why some individuals develop glaucoma while others do not. He continued to refine these techniques as a post-doc and then as a research associate at the Devers Eye Institute in Portland Oregon.
    In October 2010 he joined the University of Pittsburgh and founded the Laboratory of Ocular Biomechanics. The laboratory receives support from the National Institutes of Health, the Canadian Institutes of Health Research, The Glaucoma Research Foundation and others. Current projects in the laboratory include the development of novel techniques to characterize connective tissue architecture and biomechanics, and the study of in-vivo effects of intraocular and intracranial pressures.


    ian@ocularbiomechanics.com

 

Staff

  • Ms. Judisch

    Alexandra (Judisch) Gogola, MS - Systems Analyst

    Mrs. Gogola received a B.S.E. (2014) and M.S. (2015) in biomedical engineering from the University of Iowa. She did her graduate work on image registration and quantitative analysis of the airways in the lungs. She is using her background in computer science to provide support for several of the projects throughout the lab.



    alexandra@ocularbiomechanics.com






    • Mr. Lam

      Po Lam, BS – Research Assistant

      Mr. Lam received a BS in Biological Sciences from the University of Pittsburgh (2016). He is working on histology, image acquisition and processing.



      po@ocularbiomechanics.com




 

Post-doctoral fellows

  • Dr. Voorhees

    Andrew Voorhees, PhD - Post-doctoral fellow

    Dr. Voorhees received a B.Sc. in biology from Harvey Mudd College (2006), a M.Sc. in mechanical engineering from the University of Texas at San Antonio (2009) and a Ph.D. in Biomedical Engineering from the Joint Graduate Program at the University of Texas at San Antonio and The University of Texas Health Science Center at San Antonio (2014). Dr. Voorhees has worked on a wide range of research projects including corneal tissue engineering, computational reliability, and cardiovascular mechanics. His research focuses on understanding the role of the extracellular matrix in tissue mechanics and disease progression. His current projects focus on quantifying and modeling mechanical deformations of the lamina cribrosa due to elevated intraocular pressure.



    andrew@ocularbiomechanics.com

  • Dr. Yang

    Bin Yang, PhD - Post-doctoral fellow

    Dr. Yang received a B.Sc in Photonics from Jiangsu University/Wilfrid Laurier University (2008), a M.Sc in Optics from University of Rochester (2009), and a Ph.D. in Biomedical Engineering from the University of Texas at Austin (2015). Dr. Yang’s expertise is optical imaging on biomedical tissues. He has developed several imaging methods to quantify tissue optical and mechanical properties. Currently, his research focus is to develop polarized light imaging technology and systems to quantify collagen fiber orientation of eye tissues in 3D.



    bin@ocularbiomechanics.com

  • Dr. Brazile

    Bryn Brazile, PhD - Post-doctoral fellow

    Dr. Brazile received a B.Sc. in Biological Engineering (2009), and a Ph.D. in Biomedical Engineering (2016) from Mississippi State University. Dr. Brazile has worked on research projects spanning cardiovascular, reproductive and orthopedic biomechanics. These have included heart muscle and bone regeneration and cleft palate repair. His research interests include experimental and computational biomechanics, animal model assessments, and structure-property evaluation of soft tissues. His current projects focus on quantifying mechanical deformations of the collagen fibers in the eye due to elevated intraocular pressure.



    bryn@ocularbiomechanics.com

  • Dr. Hua

    Yi (Jason) Hua, PhD - Post-doctoral fellow

    Dr. Hua received a B.Sc. in Mechanical Engineering from Nantong University (2008), a M.Sc. in Manufacturing Engineering of Aeronautics and Astronautics from Nanjing University of Aeronautics and Astronautics (2011), and a Ph.D. in Mechanical Engineering & Applied Mechanics from the University of Nebraska-Lincoln (2016). Dr. Hua has worked on a wide range of research projects including experimental/computational analysis of traumatic brain injury, finite element modeling of optic nerve head biomechanics, mechanical characterization of soft tissues, in vitro determination of cell mechanics, and micromechanical analysis of composites. Currently, his research focus is to characterize the morphological changes of the optic nerve head in response to elevated intracranial pressure.



    jason@ocularbiomechanics.com

  • Dr. Brazile

    Junchao Wei, PhD - Post-doctoral fellow

    Dr. Wei received a B.Sc. in Mechanical Engineering from Hunan University of Technology(2011), and a Ph.D. in Mechanical Engineering from Auburn University. Dr. Wei’s primary research topic is image registration and image analysis, which including the in-vivo Digital Volume Correlation(DVC) and Digital Image Correlation(DIC) technique for soft tissues. His current research includes finding the deformation of in-vivo soft tissues, and analyzing soft tissues’ morphological change related to the elevated intraocular pressure.



    junchao@ocularbiomechanics.com

 

Graduate students

    • Ms. Jan

      Ning-Jiun Jan - PhD in Bioengineering

      Ms. Jan received a B.Sc. in Bioengineering from California Institute of Technology (2011). She is working on experimental methods for investigating ocular biomechanics in relation to glaucoma.



      ninj@ocularbiomechanics.com




    • Ms. Wang

      Bingrui Wang - Research visiting student (PhD)

      Ms. Bingrui Wang is working towards her PhD from the Southwest Jiatong University. She works on understanding the role of interwoven collagen fiber architecture on eye biomechanics.



      bingrui@ocularbiomechanics.com




    • Mr. Foong

      Tian Yong Foong - MS in Bioengineering

      Mr. Foong received a B.Sc in Mechanical Engineering from the University of Nebraska-Lincoln (2016). For his undergraduate research he worked on a stretching apparatus for Atomic Force Microscopy. He is working on experimental measures of microscale tissue mechanics.



      tian@ocularbiomechanics.com






 

Current undergraduate students

  • Eric Zhang (Summer 2017)* Co-supported by the Swanson School of Engineering

 

Former staff and students

    Staff and graduate students

  • Huong Tran (Graduate Student 2013-2017 )

  • Jake Wallace (Research Assistant 2016-2017 )

  • Rafique Khan (Research Assistant 2016 )

  • Danielle Hu (Research Assistant 2015-2016 )

  • Jonathan L. Grimm (Senior Analyst 2010-2015 )


  • Undergraduate students

  • Rachel Dunn (Summer 2017, MEMS 1043 Senior Design)

  • Roman Nilov (Summer 2017, MEMS 1043 Senior Design)

  • Noah Perryman (Summer 2017, MEMS 1043 Senior Design)

  • Ce (Ted) Zhang (Summer 2017, MEMS 1043 Senior Design)

  • Christopher Torgalski (Fall 2016 + Spring 2017)

  • Cindy Jiao (Fall 2015 - Spring 2017) * Brackenridge Fellowship by the University of Pittsburgh Honors College (Spring 2016)

  • Felipe Suntaxi (Summer+Fall 2016) * Co-supported by the Department of Bioengineering

  • Ziyi Zhu (Summer+Fall2016) * Co-supported by the Swanson School of Engineering

  • Mathew Russell (Summer 2016 - Spring 2017)

  • Morgan Austin (Summer - Spring 2017)

  • Shweta Ravichandar (Spring 2017, MEMS 1043 Senior Design)

  • Katriona Blezy (Spring 2017, MEMS 1043 Senior Design)

  • Kelly Appleton (Spring 2017, MEMS 1043 Senior Design)

  • Roy Tan Park Sung (Spring 2017, MEMS 1043 Senior Design)

  • David Bevins (Spring 2017, MEMS 1043 Senior Design)

  • Sean Boyles (Spring 2017, MEMS 1043 Senior Design)

  • Arielle Iacocca (Spring 2017, MEMS 1043 Senior Design)

  • Bryce Bowman (Spring 2017, MEMS 1043 Senior Design)

  • Ryan Oakley (Fall 2016, MEMS 1043 Senior Design)

  • Sarker Tanmoy (Fall 2016, MEMS 1043 Senior Design)

  • Lincoln Walton (Fall 2016, MEMS 1043 Senior Design)

  • Forme Balebako (Summer 2016, MEMS 1043 Senior Design)

  • Loryn Bertoti (Summer 2016, MEMS 1043 Senior Design)

  • Nicholas Neugebauer (Summer 2016, MEMS 1043 Senior Design)

  • Emma Hundertmark (Summer+Fall 2016)

  • Nicholas Krall (Summer+Fall 2016)

  • Andrew Moore (Summer+Fall2016)

  • Oliver Snyder (Summer 2016)

  • John Marshall (Summer 2016)

  • Karlie Brasch (Spring 2016, FER)

  • Jennifer Panza (Spring 2016, FER)

  • Emma Chen (Spring 2016, FER)

  • Brienna Roys (Spring 2016, FER)

  • Jin Yu Li (Spring 2016, FER)

  • Shumeng Yang (Spring 2016, FER)

  • Eric Sou Ying Dong (Spring 2016, FER)

  • Alexander Mace (Spring 2016, MEMS 1043 Senior Design)

  • Zeyu Tong (Spring 2016, Senior Design)

  • Jingxian Zhao (Spring 2016, Senior Design)

  • Joshua Selling (Fall 2015, MEMS 1043 Senior Design)

  • Morgan Skapik (Fall 2015, MEMS 1043 Senior Design)

  • Nicholas Cox (Fall 2015, MEMS 1043 Senior Design)

  • Rachel Rohr (Fall 2015, MEMS 1043 Senior Design)

  • Mikayla Ferchaw (fall 2015)

  • Michael Iasella (summer 2014, summer-fall 2015)

  • Jacob Wallace (summer 2015-spring 2016) * Brackenridge Fellowship by the University of Pittsburgh Honors College (Spring 2016)

  • Mason Lester (summer-fall 2015)

  • Andrew Levandoski (summer-fall 2015)

  • Ryan O'Malley (summer 2014-fall 2015)

  • Saundria Moed (summer 2014-spring 2015, fall 2015)* Co-supported by the Swanson School of Engineering (2014)

  • Jeremy Teichmann (summer 2015, co-mentored by Gadi Wollstein)* Co-supported by the Swanson School of Engineering (2015)

  • Yiyao Shi (summer 2015)

  • David Tsui (summer 2015)

  • Jon R. Drobitch (summer 2015)

  • Yujie Mu (summer 2015)

  • Garrett Grube (summer 2015)* Co-supported by the Department of Bioengineering (2015)

  • Zach Adgate (summer-fall 2015)

  • Jennifer Ten Eyck (summer 2015)

  • William Walters (summer 2015)

  • Sarah Smelko (summer 2014-spring 2015)

  • Natalie Rutkowski (summer 2014-spring 2015)

  • Michael Linehan (summer 2014-spring 2015)

  • Celeste Gomez (2012-2014) * Awarded a Fight for Sight summer student fellowship (2014)

  • James Constantin (summer 2014-spring 2015)* Co-supported by the Department of Bioengineering (2014)

  • Yuqi Wang (summer 2014) * Co-supported by the Department of Bioengineering (2014)

  • Aaron Dees (summer 2014)

  • Tyler Martin (summer 2014)

  • Michael Ulrich (summer 2014)

  • Yoonsoo Kim (2013-2014)

  • Sarah Shaykevich (2013-2014)